Connect Sign In
Soluble Transferrin Receptor
Ordering Recommendation
New York DOH Approval Status
Specimen Required
Serum separator tube or plasma separator tube. Also acceptable: green (lithium heparin).
Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Refrigerated.
Contaminated, severely hemolyzed, icteric, or lipemic specimens.
After separation from cells: Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month (avoid repeated freeze/thaw cycles)
Methodology
Quantitative Immunoturbidimetry
Performed
Sun-Sat
Reported
Within 24 hours
Reference Interval
Male - 18 years & older: 2.2-5.0 mg/L
Female - 18 years & older: 1.9-4.4 mg/L
Interpretive Data
People of African descent and those residing at 5,200 feet (1,600 meters) above sea level were found to have a 6% higher normal value. These differences were additive. Reference intervals have not been established for pregnant females, patients under 18 years of age, and recent or frequent blood donors.
Serum soluble transferrin receptor increases in iron deficiency and is usually unaffected by chronic disease states. In general, to increase sensitivity and specificity, the measurement of serum soluble transferrin receptor should be performed in combination with other tests of iron status, including ferritin, TIBC, and serum iron (refer to table below).
| Tests for Changes in: |
Iron Deficiency Anemia |
Anemia of Chronic Disease |
Iron Deficiency & Anemia of Chronic Disease |
|
|---|---|---|---|---|
| Ferritin | Iron Stores | Low | High | Normal or High |
| TIBC | Iron Status | High | Low | Normal or High |
| Serum Iron | Iron Status | Low | Low | Low |
| sTfR | Iron Status | High | Normal | High |
FDA
Note
Hotline History
CPT Codes
84238
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0070283 | Soluble Transferrin Receptor | 30248-9 |
Aliases
- sTfR
- TfR
- Transferrin Receptor
- Transferrin Receptor Level
